Prevalence of metabolic syndrome in adult population from Zahedan, Southeast Iran

The metabolic syndrome [MES] is associated with a high risk of diabetes and cardiovascular disease. The aim of the present study was to determine the prevalence of the metabolic syndrome as well as cut-off points for waist circumference [WC] for diagnosis of MES in Zahedan, southeast Iran. Totally, 1802 people [735 men and 1067 women] with metabolic syndrome were surveyed according to National Cholesterol Education Program Adult Treatment Panel III [NCEP ATP III] and the International Diabetes Federation [IDF] criteria as well as obtained WC cut-off points for IDF criteria. The prevalence of metabolic syndrome was higher in women than in men. In both sexes the prevalence increased with age. The prevalence of metabolic syndrome among 1802 individuals aged>/=19 years according to NCEP ATP III, IDF and IDF-AHA/NHLBI were 21.0% [15.4% in male, 24.9% female], 24.8 [20.0% in male, 28.1% in female] and 23.3% [19.7% in male, 25.8% in female], respectively. Low HDL-C [60.6%] and high WC [43.3%] were the most common components of the metabolic syndrome, followed by high triglycerides [32%], elevated glucose [17.1%] and high blood pressure [13%]. Our data shows a high prevalence of MES in Zahedan, Southeast Iran, therefore, future health prevention strategies are required for the prevention of MES

[ frequency of AgNOR [Argyrophilic Nucleoli Organizer Region] points in differentiation between the benign prostatic hyperplasia and prostatic adenocarcinoma]

Background: while the differentiation of prostatic adenocarcinoma and benign prostatic hyperplasia [BPH] is not often a difficult task, sometimes it is not the case even for the experienced pathologists. In this study the efficacy of AgNOR staining technique for differentiating between the prostatic adenocarcinoma and BPH were evaluated

Materials and Methods: using a descriptive study 15 prostatic adenocarcinoma samples [without spot to histologic grade] and 15 BPH samples were selected and stained with AgNOR method. Specimens were taken from paraffin block in Pathology laboratory archive

Results: the average AgNOR points in BPH and prostatic adenocarcinoma were1.39 and 2.48 per cell, respectively. In BPH there were one or two points of AgNOR with specific margin but in prostatic adenocarcinoma numerous arranged AgNOR points were seen. While the number of cells in BPH with three or more AgNOR points were 4.7, in prostatic adenocarcinoma it was 41.47

Conclusion: AgNOR is a useful method to differentiate between benign prostatic hyperplasia and prostatic adenocarcinoma